ChemGrid

CHEMGRID MOLECULE CARD

SU 6656

SU 6656 in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LOPAC 01339

Explore activity & SONAR
Chemical structure of SU 6656
Stored molecular structure
24Screened assays
0Significant assay responses
12Source-labelled target records

Identity and chemistry

ChemGrid identifier
LOPAC 01339
Molecular formula
C19H21N3O3S
Libraries
Lopac
Other recorded names
SU6656
Stored SMILESCN(C)S(=O)(=O)c1ccc2nc(=O)c(=Cc3nc4CCCCc4c3)c2c1

Matched external records: PubChem 5312137

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
APOBEC3F · DNA dC->dU-editing enzyme APOBEC-3FChEMBLNo stored yeast mapping
APOBEC3G · DNA dC->dU-editing enzyme APOBEC-3GChEMBLNo stored yeast mapping
AURKB · Aurora kinase BChEMBLIPL1 YPL209C (ortholog_one2many)
AURKC · Aurora kinase CChEMBLNo stored yeast mapping
BRSK2 · Serine/threonine-protein kinase BRSK2ChEMBLNo stored yeast mapping
LYN · Tyrosine-protein kinase LynChEMBLNo stored yeast mapping
SRC · Proto-oncogene tyrosine-protein kinase Src [CHEMBL267]ChEMBLNo stored yeast mapping
SRC · Proto-oncogene tyrosine-protein kinase Src [CHEMBL3655]ChEMBLNo stored yeast mapping
STK3 · Serine/threonine-protein kinase 3ChEMBLNo stored yeast mapping
TDP1 · Tyrosyl-DNA phosphodiesterase 1ChEMBLTDP1 YBR223C (ortholog_one2one)
YES1 · Tyrosine-protein kinase YesChEMBLNo stored yeast mapping
Src family kinaseChemGrid bioactivity_infoNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete SU 6656 research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.