CHEMGRID MOLECULE CARD
L-162,313
L-162,313 in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01310
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 01310
- Molecular formula
- C30H38N4O4S2
- InChIKey
- RINPELQWLUGERM-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- L-162313
Stored SMILES
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1Matched external records: PubChem 6603900
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Angiotensin type II receptor | ChEMBL | No stored yeast mapping |
| AGTR1 · Type-1 angiotensin II receptor | ChEMBL | No stored yeast mapping |
| Agtr1 · Type-1 angiotensin II receptor A | ChEMBL | No stored yeast mapping |
| Agtr1b · Angiotensin II receptor (AT-1) type-1 | ChEMBL | No stored yeast mapping |
| Agtr2 · Type-2 angiotensin II receptor | ChEMBL | No stored yeast mapping |
| ampC · Beta-lactamase | ChEMBL | No stored yeast mapping |
| Chrm1 · Muscarinic acetylcholine receptor M1 | ChEMBL | No stored yeast mapping |
| NFKB1 · Nuclear factor NF-kappa-B p105 subunit | ChEMBL | No stored yeast mapping |
| USP2 · Ubiquitin carboxyl-terminal hydrolase 2 | ChEMBL | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many) |
| Angiotensin type II receptor | ChEMBL analogue | No stored yeast mapping |
| AGTR1 · Type-1 angiotensin II receptor | ChEMBL analogue | No stored yeast mapping |
| Agtr1 · Type-1 angiotensin II receptor A | ChEMBL analogue | No stored yeast mapping |
| Agtr1b · Angiotensin II receptor (AT-1) type-1 | ChEMBL analogue | No stored yeast mapping |
| Agtr2 · Type-2 angiotensin II receptor | ChEMBL analogue | No stored yeast mapping |
| ampC · Beta-lactamase | ChEMBL analogue | No stored yeast mapping |
| Chrm1 · Muscarinic acetylcholine receptor M1 | ChEMBL analogue | No stored yeast mapping |
| NFKB1 · Nuclear factor NF-kappa-B p105 subunit | ChEMBL analogue | No stored yeast mapping |
| USP2 · Ubiquitin carboxyl-terminal hydrolase 2 | ChEMBL analogue | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many) |
| AT1 | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete L-162,313 research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.