CHEMGRID MOLECULE CARD
Vincristine sulfate
Vincristine sulfate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01290
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 01290
- Molecular formula
- C46H58N4O14S
- Libraries
- Lopac
- Other recorded names
- Vincristine Sulfate
Stored SMILES
CCC1(O)CC2CN(CCc3c(nc4ccccc43)C(C2)(C(=O)OC)c2cc3c(cc2OC)N(C=O)C2C(O)(C(OC(C)=O)C4(CC)C=CCN5CCC23C54)C(=O)OC)C1.OS(O)(=O)=OMatched external records: PubChem 249332
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Tubulin | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Vincristine sulfate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.