CHEMGRID MOLECULE CARD
T-0156
T-0156 in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01275
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 01275
- Molecular formula
- C31ClH30N5O7
- InChIKey
- RBJCBXAXUHCWBR-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- T 0156 hydrochloride
Stored SMILES
Cl.COC(=O)C1N(Cc2ccnc(C)c2)C(=O)c2c(OCc3ncccn3)nccc2C=1c1cc(OC)c(OC)c(OC)c1Matched external records: PubChem 9852041
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Cruzipain | ChEMBL | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL | SGS1 YMR190C (ortholog_one2one) |
| NPSR1 · Neuropeptide S receptor | ChEMBL | No stored yeast mapping |
| PDE1A · Phosphodiesterase 1 | ChEMBL | No stored yeast mapping |
| PDE2A · cGMP-dependent 3',5'-cyclic phosphodiesterase | ChEMBL | No stored yeast mapping |
| PDE4A · Phosphodiesterase 4 | ChEMBL | No stored yeast mapping |
| PDE5A · cGMP-specific 3',5'-cyclic phosphodiesterase | ChEMBL | No stored yeast mapping |
| PDE6B · Phosphodiesterase 6 | ChEMBL | No stored yeast mapping |
| PMP22 · Peripheral myelin protein 22 | ChEMBL | No stored yeast mapping |
| PDE V | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete T-0156 research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.