CHEMGRID MOLECULE CARD

(-)-Scopolamine methyl nitrate

(-)-Scopolamine methyl nitrate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LOPAC 01207

Explore activity & SONAR

Chemical structure of (-)-Scopolamine methyl nitrate — Stored molecular structure

24Screened assays

0Significant assay responses

10Source-labelled target records

Identity and chemistry

ChemGrid identifier: LOPAC 01207
Molecular formula: C18H24N2O7
InChIKey: BSQIVYOSLFLSGE-UHFFFAOYSA-N
Libraries: Lopac
Other recorded names: Scopolamine methyl nitrate

Stored SMILES

[O-][N+]([O-])=O.C[N+]1(C)C2CC(CC1C1OC12)OC(=O)C(CO)c1ccccc1

Matched external records: PubChem 12906333

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
EHMT2 · Histone-lysine N-methyltransferase EHMT2	ChEMBL	SET2 YJL168C (ortholog_many2many)
MPHOSPH8 · M-phase phosphoprotein 8	ChEMBL	No stored yeast mapping
Txnrd1 · Thioredoxin reductase 1, cytoplasmic	ChEMBL	TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many)
BLM · RecQ-like DNA helicase BLM	ChEMBL analogue	SGS1 YMR190C (ortholog_one2one)
CBX1 · Chromobox protein homolog 1	ChEMBL analogue	No stored yeast mapping
GNAS · Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	ChEMBL analogue	GPA2 YER020W (ortholog_many2many); GPA1 YHR005C (ortholog_many2many)
MEN1 · Menin/Histone-lysine N-methyltransferase MLL	ChEMBL analogue	No stored yeast mapping
nfo · Endonuclease 4	ChEMBL analogue	No stored yeast mapping
RAPGEF3 · Rap guanine nucleotide exchange factor 3	ChEMBL analogue	LTE1 YAL024C (ortholog_many2many); CDC25 YLR310C (ortholog_many2many)
Muscarinic	ChemGrid bioactivity_info	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete (-)-Scopolamine methyl nitrate research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.