CHEMGRID MOLECULE CARD
Reactive Blue 2
Reactive Blue 2 in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01195
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 01195
- Molecular formula
- C29ClH17N7Na3O11S3
- InChIKey
- WDPGNDHCHKUGLY-UHFFFAOYSA-K
- Libraries
- Lopac
- Other recorded names
- Blue FPG-A
Stored SMILES
[Na+].[Na+].[Na+].[O-]S(=O)(=O)c1ccc(Nc2nc(Cl)nc(Nc3ccc(Nc4cc(c(N)c5c(=O)c6ccccc6c(=O)c45)S([O-])(=O)=O)cc3S([O-])(=O)=O)n2)cc1Matched external records: PubChem 6604161
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| grpE · Protein GrpE | ChEMBL | MGE1 YOR232W (ortholog_one2many) |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| MPHOSPH8 · M-phase phosphoprotein 8 | ChEMBL | No stored yeast mapping |
| NPSR1 · Neuropeptide S receptor | ChEMBL | No stored yeast mapping |
| P2RY4 · P2Y purinoceptor 4 | ChEMBL | No stored yeast mapping |
| POLB · DNA polymerase beta | ChEMBL | No stored yeast mapping |
| PYK · Pyruvate kinase | ChEMBL | No stored yeast mapping |
| RECQL · ATP-dependent DNA helicase Q1 | ChEMBL | No stored yeast mapping |
| THPO · Thrombopoietin | ChEMBL | No stored yeast mapping |
| P2Y | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Reactive Blue 2 research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.