CHEMGRID MOLECULE CARD
Quercetin dihydrate
Quercetin dihydrate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01176
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 01176
- Molecular formula
- C15H10O7
- InChIKey
- REFJWTPEDVJJIY-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- Quercetin
Stored SMILES
Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c1ccc(O)c(O)c1Matched external records: PubChem 5280343
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ABCG2 · Broad substrate specificity ATP-binding cassette transporter ABCG2 | ChEMBL | SNQ2 YDR011W (ortholog_many2many); PDR15 YDR406W (ortholog_many2many); PDR11 YIL013C (ortholog_many2many); YNR070W (ortholog_many2many); AUS1 YOR011W (ortholog_many2many); PDR5 YOR153W (ortholog_many2many); PDR10 YOR328W (ortholog_many2many); PDR12 YPL058C (ortholog_many2many) |
| AKR1B1 · Aldo-keto reductase family 1 member B1 | ChEMBL | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| CYP19A1 · Aromatase | ChEMBL | No stored yeast mapping |
| CYP1B1 · Cytochrome P450 1B1 | ChEMBL | No stored yeast mapping |
| F2 · Prothrombin | ChEMBL | No stored yeast mapping |
| fabI · Enoyl-acyl-carrier protein reductase | ChEMBL | No stored yeast mapping |
| MAOA · Amine oxidase [flavin-containing] A | ChEMBL | No stored yeast mapping |
| Nt5e · 5'-nucleotidase | ChEMBL | YHR202W (ortholog_one2one) |
| PIM1 · Serine/threonine-protein kinase pim-1 | ChEMBL | PIM1 YBL022C (ortholog_one2many) |
| SRC · Proto-oncogene tyrosine-protein kinase Src | ChEMBL | No stored yeast mapping |
| ABCG2 · Broad substrate specificity ATP-binding cassette transporter ABCG2 | ChEMBL analogue | SNQ2 YDR011W (ortholog_many2many); PDR15 YDR406W (ortholog_many2many); PDR11 YIL013C (ortholog_many2many); YNR070W (ortholog_many2many); AUS1 YOR011W (ortholog_many2many); PDR5 YOR153W (ortholog_many2many); PDR10 YOR328W (ortholog_many2many); PDR12 YPL058C (ortholog_many2many) |
| ACHE · Acetylcholinesterase | ChEMBL analogue | No stored yeast mapping |
| AKR1B1 · Aldo-keto reductase family 1 member B1 | ChEMBL analogue | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| ALOX12 · Polyunsaturated fatty acid lipoxygenase ALOX12 | ChEMBL analogue | No stored yeast mapping |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL analogue | No stored yeast mapping |
| ALOX15B · Polyunsaturated fatty acid lipoxygenase ALOX15B | ChEMBL analogue | No stored yeast mapping |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| APP · Amyloid-beta precursor protein | ChEMBL analogue | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL analogue | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL analogue | No stored yeast mapping |
| CA7 · Carbonic anhydrase 7 | ChEMBL analogue | No stored yeast mapping |
| CASP1 · Caspase-1 | ChEMBL analogue | No stored yeast mapping |
| CASP7 · Caspase-7 | ChEMBL analogue | No stored yeast mapping |
| CDK1 · Cyclin-dependent kinase 1/cyclin B | ChEMBL analogue | CDC28 YBR160W (ortholog_one2many) |
| CDK5 · Cyclin-dependent kinase 5/CDK5 activator 1 | ChEMBL analogue | No stored yeast mapping |
| CDK6 · Cyclin-dependent kinase 6 | ChEMBL analogue | No stored yeast mapping |
| Chrm1 · Muscarinic acetylcholine receptor M1 | ChEMBL analogue | No stored yeast mapping |
| CSNK2A1 · Casein kinase II subunit alpha | ChEMBL analogue | CKA1 YIL035C (ortholog_many2many); CKA2 YOR061W (ortholog_many2many) |
| CSNK2B · Casein kinase 2 | ChEMBL analogue | No stored yeast mapping |
| CSNK2B · Casein kinase II | ChEMBL analogue | No stored yeast mapping |
First 30 of 77 target records; open the interactive profile for further evidence.
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Quercetin dihydrate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.