CHEMGRID MOLECULE CARD
Pentolinium di[L(+)-tartrate]
Pentolinium di[L(+)-tartrate] in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01132
Explore activity & SONAR![Chemical structure of Pentolinium di[L(+)-tartrate]](/structure-thumbnails/Lopac/LO/LOPAC_01132.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- LOPAC 01132
- Molecular formula
- C23H42N2O12
- InChIKey
- HSMKTIKKPMTUQH-UHFFFAOYSA-L
- Libraries
- Lopac
- Other recorded names
- Pentolinium bitartrate
Stored SMILES
[O-]C(=O)C(O)C(O)C(O)=O.[O-]C(=O)C(O)C(O)C(O)=O.C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1Matched external records: PubChem 5702277
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| RUNX1 · Runt-related transcription factor 1/Core-binding factor subunit beta | ChEMBL | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL analogue | SGS1 YMR190C (ortholog_one2one) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| GMNN · Geminin | ChEMBL analogue | No stored yeast mapping |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL analogue | YJR119C (ortholog_one2many) |
| NFKB1 · Nuclear factor NF-kappa-B p105 subunit | ChEMBL analogue | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| RUNX1 · Runt-related transcription factor 1/Core-binding factor subunit beta | ChEMBL analogue | No stored yeast mapping |
| TARDBP · TAR DNA-binding protein 43 | ChEMBL analogue | PIN4 YBL051C (ortholog_many2many) |
| TSHR · Thyrotropin receptor | ChEMBL analogue | No stored yeast mapping |
| Nicotinic | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Pentolinium di[L(+)-tartrate] research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.