CHEMGRID MOLECULE CARD
Piceatannol
Piceatannol in ChemGrid: 24 screened assays, 1 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 01122
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 01122
- Molecular formula
- C14H12O4
- InChIKey
- CDRPUGZCRXZLFL-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- 4-(2-(3,5-Dihydroxyphenyl)Ethenyl)Benzene-1,2-Diol
Stored SMILES
Oc1cc(O)cc(C=Cc2ccc(O)c(O)c2)c1Matched external records: PubChem 4813
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 1 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| NOP13 | Lopac | 4932 | -12.81 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALK · ALK tyrosine kinase receptor | ChEMBL | No stored yeast mapping |
| CAMKK2 · Calcium/calmodulin-dependent protein kinase kinase 2 | ChEMBL | SAK1 YER129W (ortholog_one2many); TOS3 YGL179C (ortholog_one2many) |
| DYRK1A · Dual specificity tyrosine-phosphorylation-regulated kinase 1A | ChEMBL | No stored yeast mapping |
| DYRK1B · Dual specificity tyrosine-phosphorylation-regulated kinase 1B | ChEMBL | No stored yeast mapping |
| MAP3K10 · Mitogen-activated protein kinase kinase kinase 10 | ChEMBL | No stored yeast mapping |
| MAPK10 · Mitogen-activated protein kinase 10 | ChEMBL | No stored yeast mapping |
| MARK3 · MAP/microtubule affinity-regulating kinase 3 | ChEMBL | No stored yeast mapping |
| MARK4 · MAP/microtubule affinity-regulating kinase 4 | ChEMBL | No stored yeast mapping |
| MELK · Maternal embryonic leucine zipper kinase | ChEMBL | YPL150W (ortholog_one2one) |
| ROCK2 · Rho-associated protein kinase 2 | ChEMBL | No stored yeast mapping |
| SIK2 · Serine/threonine-protein kinase SIK2 | ChEMBL | PRR2 YDL214C (ortholog_many2many); KIN1 YDR122W (ortholog_many2many); VHS1 YDR247W (ortholog_many2many); HAL5 YJL165C (ortholog_many2many); PTK2 YJR059W (ortholog_many2many); KKQ8 YKL168C (ortholog_many2many); PTK1 YKL198C (ortholog_many2many); KIN2 YLR096W (ortholog_many2many); NPR1 YNL183C (ortholog_many2many); KIN4 YOR233W (ortholog_many2many); SKS1 YPL026C (ortholog_many2many); YPL141C (ortholog_many2many) |
| TYRO3 · Tyrosine-protein kinase receptor TYRO3 | ChEMBL | No stored yeast mapping |
| CA1 · Carbonic anhydrase 1 | ChEMBL analogue | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL analogue | No stored yeast mapping |
| CA13 · Carbonic anhydrase 13 | ChEMBL analogue | No stored yeast mapping |
| CA14 · Carbonic anhydrase 14 | ChEMBL analogue | No stored yeast mapping |
| Ca15 · Carbonic anhydrase 15 | ChEMBL analogue | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL analogue | No stored yeast mapping |
| CA3 · Carbonic anhydrase 3 | ChEMBL analogue | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL analogue | No stored yeast mapping |
| CA5A · Carbonic anhydrase 5A, mitochondrial | ChEMBL analogue | No stored yeast mapping |
| CA5B · Carbonic anhydrase 5B, mitochondrial | ChEMBL analogue | No stored yeast mapping |
| CA6 · Carbonic anhydrase 6 | ChEMBL analogue | No stored yeast mapping |
| Syk / Lck | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Piceatannol research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.