CHEMGRID MOLECULE CARD

Oxiracetam

Oxiracetam in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LOPAC 01109

Explore activity & SONAR

Chemical structure of Oxiracetam — Stored molecular structure

24Screened assays

0Significant assay responses

10Source-labelled target records

Identity and chemistry

ChemGrid identifier: LOPAC 01109
Molecular formula: C6H10N2O3
InChIKey: IHLAQQPQKRMGSS-UHFFFAOYSA-N
Libraries: Lopac

Stored SMILES

NC(=O)CN1CC(O)CC1=O

Matched external records: PubChem 4626

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
APEX1 · DNA repair nuclease/redox regulator APEX1	ChEMBL	No stored yeast mapping
ARSA · Arylsulfatase A	ChEMBL	No stored yeast mapping
BLM · RecQ-like DNA helicase BLM	ChEMBL	SGS1 YMR190C (ortholog_one2one)
EHMT2 · Histone-lysine N-methyltransferase EHMT2	ChEMBL	SET2 YJL168C (ortholog_many2many)
HRH1 · Histamine H1 receptor	ChEMBL	PRP22 YER013W (ortholog_one2one)
MPHOSPH8 · M-phase phosphoprotein 8	ChEMBL	No stored yeast mapping
pfk · ATP-dependent 6-phosphofructokinase	ChEMBL	No stored yeast mapping
rep · Replicase polyprotein 1ab	ChEMBL	No stored yeast mapping
Txnrd1 · Thioredoxin reductase 1, cytoplasmic	ChEMBL	TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many)
.	ChemGrid bioactivity_info	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete Oxiracetam research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.