CHEMGRID MOLECULE CARD
Methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate
Methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00903
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00903
- Molecular formula
- C17H18N2O4
- Libraries
- Lopac
- Other recorded names
- Methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carb; methyl 4-ethyl-6,7-dimethoxy-9H-pyrido(3,4-b)indole-3-carboxylate
Stored SMILES
CCc1c(ncc2nc3cc(OC)c(OC)cc3c21)C(=O)OCMatched external records: PubChem 104999
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| AKR1B1 · Aldo-keto reductase family 1 member B1 | ChEMBL | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| Agonist | ChemGrid bioactivity_info | No stored yeast mapping |
| CAR | lopac_target_list | No stored yeast mapping |
| ADRBK1 · beta | lopac_target_list | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.