CHEMGRID MOLECULE CARD
N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00860
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00860
- Molecular formula
- C28FH37N2O
- Libraries
- Lopac
- Other recorded names
- 2-(4-Fluorophenyl)-N,N-dihexyl-1H-indole-3-acetamide
Stored SMILES
CCCCCCN(CCCCCC)C(=O)Cc1c(nc2ccccc12)c1ccc(F)cc1Matched external records: PubChem 132496
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Adrenergic receptor alpha | ChEMBL | No stored yeast mapping |
| Adrenergic receptor beta | ChEMBL | No stored yeast mapping |
| GABA-A receptor; anion channel | ChEMBL | No stored yeast mapping |
| Glutamate NMDA receptor | ChEMBL | No stored yeast mapping |
| Opioid receptor | ChEMBL | No stored yeast mapping |
| Serotonin 1 (5-HT1) receptor | ChEMBL | No stored yeast mapping |
| Cckbr · Gastrin/cholecystokinin type B receptor | ChEMBL | No stored yeast mapping |
| Cnr1 · Cannabinoid receptor 1 | ChEMBL | No stored yeast mapping |
| Tspo · Translocator protein [CHEMBL2149] | ChEMBL | No stored yeast mapping |
| Tspo · Translocator protein [CHEMBL4552] | ChEMBL | No stored yeast mapping |
| TSPO · Translocator protein [CHEMBL5742] | ChEMBL | No stored yeast mapping |
| Mitochondria | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.