CHEMGRID MOLECULE CARD
O-(Carboxymethyl)hydroxylamine hemihydrochloride
O-(Carboxymethyl)hydroxylamine hemihydrochloride in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00669
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00669
- Molecular formula
- C4ClH11N2O6
- InChIKey
- KBXIJIPYZKPDRU-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- Aminooxyacetic acid hemihydrochloride
Stored SMILES
Cl.NOCC(O)=O.NOCC(O)=OMatched external records: PubChem 2723609
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| NS1 · Nonstructural protein 1 | ChEMBL | No stored yeast mapping |
| THRB · Thyroid hormone receptor beta | ChEMBL | No stored yeast mapping |
| Abat · 4-aminobutyrate aminotransferase, mitochondrial | ChEMBL analogue | UGA1 YGR019W (ortholog_one2one) |
| ARSA · Arylsulfatase A | ChEMBL analogue | No stored yeast mapping |
| CBS · Cystathionine beta-synthase | ChEMBL analogue | CYS4 YGR155W (ortholog_one2one) |
| Chrm1 · Muscarinic acetylcholine receptor M1 | ChEMBL analogue | No stored yeast mapping |
| CTH · Cystathionine gamma-lyase | ChEMBL analogue | CYS3 YAL012W (ortholog_one2one) |
| DRD1 · D(1A) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| KAT2A · Histone acetyltransferase KAT2A | ChEMBL analogue | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| THPO · Thrombopoietin | ChEMBL analogue | No stored yeast mapping |
| TSHR · Thyrotropin receptor | ChEMBL analogue | No stored yeast mapping |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL analogue | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
| Aminotransferase | ChemGrid bioactivity_info | No stored yeast mapping |
| CAR | lopac_target_list | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete O-(Carboxymethyl)hydroxylamine hemihydrochloride research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.