CHEMGRID MOLECULE CARD
3-Amino-1-propanesulfonic acid sodium
3-Amino-1-propanesulfonic acid sodium in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00656
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00656
- Molecular formula
- C3H8NNaO3S
- InChIKey
- KMGJRCNLDZGSFX-UHFFFAOYSA-M
- Libraries
- Lopac
- Other recorded names
- Tramiprosate Sodium
Stored SMILES
[Na+].[O-]S(=O)(=O)CCCNMatched external records: PubChem 23663660
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| HBB · Hemoglobin subunit beta | ChEMBL | No stored yeast mapping |
| Impa1 · Inositol monophosphatase 1 | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| THPO · Thrombopoietin | ChEMBL | No stored yeast mapping |
| TP53 · Cellular tumor antigen p53 | ChEMBL | No stored yeast mapping |
| TSHR · Thyrotropin receptor | ChEMBL | No stored yeast mapping |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| APP · Amyloid-beta precursor protein | ChEMBL analogue | No stored yeast mapping |
| ATAD5 · ATPase family AAA domain-containing protein 5 | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| Gabbr1 · GABA B receptor | ChEMBL analogue | No stored yeast mapping |
| Gabrp · GABA-A receptor; anion channel | ChEMBL analogue | No stored yeast mapping |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL analogue | No stored yeast mapping |
| pfk · ATP-dependent 6-phosphofructokinase | ChEMBL analogue | No stored yeast mapping |
| SLC36A1 · Proton-coupled amino acid transporter 1 | ChEMBL analogue | AVT5 YBL089W (ortholog_many2many); AVT6 YER119C (ortholog_many2many); AVT1 YJR001W (ortholog_many2many); AVT4 YNL101W (ortholog_many2many) |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL analogue | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
| GABA-A | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 3-Amino-1-propanesulfonic acid sodium research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.