CHEMGRID MOLECULE CARD
5-Carboxamidotryptamine maleate
5-Carboxamidotryptamine maleate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00498
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00498
- Molecular formula
- C15H17N3O5
- Libraries
- Lopac
Stored SMILES
NCCc1cnc2ccc(cc12)C(N)=O.OC(=O)C=CC(O)=OMatched external records: PubChem 11709509
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADRA2A · Alpha-2A adrenergic receptor | ChEMBL | No stored yeast mapping |
| DRD2 · D(2) dopamine receptor | ChEMBL | No stored yeast mapping |
| HTR1A · 5-hydroxytryptamine receptor 1A | ChEMBL | No stored yeast mapping |
| HTR1B · 5-hydroxytryptamine receptor 1B | ChEMBL | No stored yeast mapping |
| HTR1D · 5-hydroxytryptamine receptor 1D | ChEMBL | No stored yeast mapping |
| HTR1E · 5-hydroxytryptamine receptor 1E | ChEMBL | No stored yeast mapping |
| HTR2B · 5-hydroxytryptamine receptor 2B | ChEMBL | No stored yeast mapping |
| HTR2C · 5-hydroxytryptamine receptor 2C | ChEMBL | No stored yeast mapping |
| HTR5A · 5-hydroxytryptamine receptor 5A | ChEMBL | No stored yeast mapping |
| HTR6 · 5-hydroxytryptamine receptor 6 | ChEMBL | No stored yeast mapping |
| HTR7 · 5-hydroxytryptamine receptor 7 | ChEMBL | No stored yeast mapping |
| TMEM97 · Sigma intracellular receptor 2 | ChEMBL | YLR050C (ortholog_one2one) |
| 5-HT7 | ChemGrid bioactivity_info | No stored yeast mapping |
| CAR | lopac_target_list | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 5-Carboxamidotryptamine maleate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.