CHEMGRID MOLECULE CARD
D-609 potassium
D-609 potassium in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00428
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00428
- Molecular formula
- C11H15KOS2
- InChIKey
- IGULCCCBGBDZKQ-UHFFFAOYSA-M
- Libraries
- Lopac
- Other recorded names
- Potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate
Stored SMILES
[K+].[S-]C(=S)OC1CC2CC1C1CCCC21Matched external records: PubChem 4234241
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALDH1A1 · Aldehyde dehydrogenase 1A1 | ChEMBL | ALD5 YER073W (ortholog_many2many); ALD3 YMR169C (ortholog_many2many); ALD2 YMR170C (ortholog_many2many); ALD4 YOR374W (ortholog_many2many); ALD6 YPL061W (ortholog_many2many) |
| BLM · RecQ-like DNA helicase BLM | ChEMBL | SGS1 YMR190C (ortholog_one2one) |
| CA1 · Carbonic anhydrase 1 | ChEMBL | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL | No stored yeast mapping |
| CA9 · Carbonic anhydrase 9 | ChEMBL | No stored yeast mapping |
| FTL · Ferritin light chain | ChEMBL | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| MPHOSPH8 · M-phase phosphoprotein 8 | ChEMBL | No stored yeast mapping |
| nfo · Endonuclease 4 | ChEMBL | No stored yeast mapping |
| VDR · Vitamin D3 receptor | ChEMBL | No stored yeast mapping |
| PIPLC | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete D-609 potassium research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.