CHEMGRID MOLECULE CARD
Fenofibrate
Fenofibrate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00410
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00410
- Molecular formula
- C20ClH21O4
- InChIKey
- YMTINGFKWWXKFG-UHFFFAOYSA-N
- Libraries
- Lopac
Stored SMILES
CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1Matched external records: PubChem 3339
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Chrm1 · Muscarinic acetylcholine receptor M1 | ChEMBL | No stored yeast mapping |
| CNR1 · Cannabinoid receptor 1 | ChEMBL | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| Fabp1 · Fatty acid-binding protein, liver | ChEMBL | No stored yeast mapping |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| HTR2C · 5-hydroxytryptamine receptor 2C | ChEMBL | No stored yeast mapping |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL | YJR119C (ortholog_one2many) |
| MPHOSPH8 · M-phase phosphoprotein 8 | ChEMBL | No stored yeast mapping |
| PPARA · Peroxisome proliferator-activated receptor alpha | ChEMBL | No stored yeast mapping |
| PPARG · Peroxisome proliferator-activated receptor gamma | ChEMBL | No stored yeast mapping |
| Chrm1 · Muscarinic acetylcholine receptor M1 | ChEMBL analogue | No stored yeast mapping |
| CNR1 · Cannabinoid receptor 1 | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| Fabp1 · Fatty acid-binding protein, liver | ChEMBL analogue | No stored yeast mapping |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL analogue | No stored yeast mapping |
| HTR2C · 5-hydroxytryptamine receptor 2C | ChEMBL analogue | No stored yeast mapping |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL analogue | YJR119C (ortholog_one2many) |
| MPHOSPH8 · M-phase phosphoprotein 8 | ChEMBL analogue | No stored yeast mapping |
| PPARA · Peroxisome proliferator-activated receptor alpha | ChEMBL analogue | No stored yeast mapping |
| PPARG · Peroxisome proliferator-activated receptor gamma | ChEMBL analogue | No stored yeast mapping |
| PPAR-alpha | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Fenofibrate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.