CHEMGRID MOLECULE CARD
NBQX disodium
NBQX disodium in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00386
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00386
- Molecular formula
- C12H6N4Na2O6S
- InChIKey
- SVJKYIUJRJEABK-UHFFFAOYSA-L
- Libraries
- Lopac
- Other recorded names
- NBQX disodium salt
Stored SMILES
[Na+].[Na+].[O-]c1nc2cc(c3c(cccc3S(N)(=O)=O)c2nc1[O-])[N+]([O-])=OMatched external records: PubChem 6098006
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ampC · Beta-lactamase | ChEMBL | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| HPGD · 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | ChEMBL | AYR1 YIL124W (ortholog_one2one) |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| PABPC1 · Polyadenylate-binding protein 1 | ChEMBL | No stored yeast mapping |
| PKM · Pyruvate kinase PKM | ChEMBL | CDC19 YAL038W (ortholog_many2many); PYK2 YOR347C (ortholog_many2many) |
| POLI · DNA polymerase iota | ChEMBL | No stored yeast mapping |
| PYK · Pyruvate kinase | ChEMBL | No stored yeast mapping |
| TP53 · Cellular tumor antigen p53 | ChEMBL | No stored yeast mapping |
| AMPA/kainate | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete NBQX disodium research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.