CHEMGRID MOLECULE CARD
(±)-Sulpiride
(±)-Sulpiride in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00308
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00308
- Molecular formula
- C15H23N3O4S
- InChIKey
- BGRJTUBHPOOWDU-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- (±)-Sulpiride; Sulpiride
Stored SMILES
CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=OMatched external records: PubChem 5355
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| 1272966 · AGAP002992-PA | ChEMBL | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL | SGS1 YMR190C (ortholog_one2one) |
| CA1 · Carbonic anhydrase 1 | ChEMBL | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL | No stored yeast mapping |
| CA5B · Carbonic anhydrase 5B, mitochondrial | ChEMBL | No stored yeast mapping |
| CA6 · Carbonic anhydrase 6 | ChEMBL | No stored yeast mapping |
| CA7 · Carbonic anhydrase 7 | ChEMBL | No stored yeast mapping |
| CA9 · Carbonic anhydrase 9 | ChEMBL | No stored yeast mapping |
| DRD2 · D(2) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD3 · D(3) dopamine receptor | ChEMBL | No stored yeast mapping |
| 1272966 · AGAP002992-PA | ChEMBL analogue | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL analogue | SGS1 YMR190C (ortholog_one2one) |
| CA1 · Carbonic anhydrase 1 | ChEMBL analogue | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL analogue | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL analogue | No stored yeast mapping |
| CA5B · Carbonic anhydrase 5B, mitochondrial | ChEMBL analogue | No stored yeast mapping |
| CA6 · Carbonic anhydrase 6 | ChEMBL analogue | No stored yeast mapping |
| CA7 · Carbonic anhydrase 7 | ChEMBL analogue | No stored yeast mapping |
| CA9 · Carbonic anhydrase 9 | ChEMBL analogue | No stored yeast mapping |
| DRD2 · D(2) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| DRD3 · D(3) dopamine receptor | ChEMBL analogue | No stored yeast mapping |
| DRD2 | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete (±)-Sulpiride research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.