CHEMGRID MOLECULE CARD
R(+)-Lisuride hydrogen maleate
R(+)-Lisuride hydrogen maleate in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00289
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00289
- Molecular formula
- C24H30N4O5
- Libraries
- Lopac
- Other recorded names
- Lisuride
Stored SMILES
CCN(CC)C(=O)NC1CN(C)C2Cc3cnc4cccc(C2=C1)c34.OC(=O)C=CC(O)=OMatched external records: PubChem 28864
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADRA2A · Alpha-2A adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRA2B · Alpha-2B adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRA2C · Alpha-2C adrenergic receptor | ChEMBL | No stored yeast mapping |
| DRD1 · D(1A) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD2 · D(2) dopamine receptor [CHEMBL217] | ChEMBL | No stored yeast mapping |
| Drd2 · D(2) dopamine receptor [CHEMBL339] | ChEMBL | No stored yeast mapping |
| DRD3 · D(3) dopamine receptor | ChEMBL | No stored yeast mapping |
| DRD4 · D(4) dopamine receptor | ChEMBL | No stored yeast mapping |
| HTR1A · 5-hydroxytryptamine receptor 1A [CHEMBL214] | ChEMBL | No stored yeast mapping |
| Htr1a · 5-hydroxytryptamine receptor 1A [CHEMBL273] | ChEMBL | No stored yeast mapping |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| HTR2B · 5-hydroxytryptamine receptor 2B | ChEMBL | No stored yeast mapping |
| DRD2 | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete R(+)-Lisuride hydrogen maleate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.