CHEMGRID MOLECULE CARD
N6-Methyladenosine
N6-Methyladenosine in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00050
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00050
- Molecular formula
- C11H15N5O4
- InChIKey
- VQAYFKKCNSOZKM-UHFFFAOYSA-N
- Libraries
- Lopac
- Other recorded names
- N-Methyl-9-pentofuranosyl-9H-purin-6-amine
Stored SMILES
CNc1ncnc2n(cnc12)C1OC(CO)C(O)C1OMatched external records: PubChem 1869
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Luciferin 4-monooxygenase | ChEMBL analogue | No stored yeast mapping |
| AVPR1B · Vasopressin V1b receptor | ChEMBL analogue | No stored yeast mapping |
| HIF1A · Hypoxia-inducible factor 1-alpha | ChEMBL analogue | No stored yeast mapping |
| HTT · Huntingtin | ChEMBL analogue | No stored yeast mapping |
| RXFP1 · Relaxin receptor 1 | ChEMBL analogue | No stored yeast mapping |
| RXFP2 · Relaxin receptor 2 | ChEMBL analogue | No stored yeast mapping |
| SLC5A7 · High affinity choline transporter 1 | ChEMBL analogue | DUR3 YHL016C (ortholog_one2many) |
| Agonist | ChemGrid bioactivity_info | No stored yeast mapping |
| NOS3 · NOS | lopac_target_list | MET10 YFR030W (ortholog_many2many); ECM17 YJR137C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete N6-Methyladenosine research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.