CHEMGRID MOLECULE CARD
Dipyridamole
Dipyridamole in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00035
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00035
- Molecular formula
- C24H40N8O4
- InChIKey
- IZEKFCXSFNUWAM-UHFFFAOYSA-N
- Libraries
- Lopac
Stored SMILES
OCCN(CCO)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCO)CCOMatched external records: PubChem 3108
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| PDE11A · Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | ChEMBL | No stored yeast mapping |
| PDE4A · Phosphodiesterase 4 | ChEMBL | No stored yeast mapping |
| PDE5A · cGMP-specific 3',5'-cyclic phosphodiesterase | ChEMBL | No stored yeast mapping |
| PDE6H · Phosphodiesterase 6 | ChEMBL | No stored yeast mapping |
| PDE7A · Phosphodiesterase 7 | ChEMBL | No stored yeast mapping |
| PRUNE1 · Exopolyphosphatase PRUNE1 | ChEMBL | PPX1 YHR201C (ortholog_one2one) |
| rep · Replicase polyprotein 1ab | ChEMBL | No stored yeast mapping |
| SLC29A1 · Equilibrative nucleoside transporter 1 | ChEMBL | FUN26 YAL022C (ortholog_one2many) |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
| LMNA · Prelamin-A/C | ChEMBL analogue | No stored yeast mapping |
| PDE11A · Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | ChEMBL analogue | No stored yeast mapping |
| PDE4A · Phosphodiesterase 4 | ChEMBL analogue | No stored yeast mapping |
| PDE5A · cGMP-specific 3',5'-cyclic phosphodiesterase | ChEMBL analogue | No stored yeast mapping |
| PDE6H · Phosphodiesterase 6 | ChEMBL analogue | No stored yeast mapping |
| PDE7A · Phosphodiesterase 7 | ChEMBL analogue | No stored yeast mapping |
| PRUNE1 · Exopolyphosphatase PRUNE1 | ChEMBL analogue | PPX1 YHR201C (ortholog_one2one) |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| SLC29A1 · Equilibrative nucleoside transporter 1 | ChEMBL analogue | FUN26 YAL022C (ortholog_one2many) |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
| Inhibitor | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Dipyridamole research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.