CHEMGRID MOLECULE CARD
8-(p-Sulfophenyl)theophylline
8-(p-Sulfophenyl)theophylline in ChemGrid: 24 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LOPAC 00009
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LOPAC 00009
- Molecular formula
- C13H12N4O5S
- Libraries
- Lopac
Stored SMILES
CN1C(=O)N(C)c2nc(nc2C1=O)c1ccc(cc1)S(O)(=O)=OMatched external records: PubChem 1908
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
24 measurements across 24 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Adenosine A2 receptor [CHEMBL2094117] | ChEMBL | No stored yeast mapping |
| Adenosine A2 receptor [CHEMBL2094257] | ChEMBL | No stored yeast mapping |
| ADORA1 · Adenosine receptor A1 [CHEMBL226] | ChEMBL | No stored yeast mapping |
| Adora1 · Adenosine receptor A1 [CHEMBL318] | ChEMBL | No stored yeast mapping |
| ADORA1 · Adenosine receptor A1 [CHEMBL4975] | ChEMBL | No stored yeast mapping |
| ADORA2A · Adenosine receptor A2a [CHEMBL2605] | ChEMBL | No stored yeast mapping |
| Adora2a · Adenosine receptor A2a [CHEMBL302] | ChEMBL | No stored yeast mapping |
| ADORA2B · Adenosine receptor A2b | ChEMBL | No stored yeast mapping |
| ADORA3 · Adenosine receptor A3 | ChEMBL | No stored yeast mapping |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL | No stored yeast mapping |
| A1 > A2 | ChemGrid bioactivity_info | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 8-(p-Sulfophenyl)theophylline research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.