CHEMGRID MOLECULE CARD
2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-N-(4-methoxyphenyl)acetamide
2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-N-(4-methoxyphenyl)acetamide in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT026H10
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT026H10
- Molecular formula
- C18H16N2O4
- InChIKey
- PWXBFIKCATUTKC-UHFFFAOYSA-N
- Libraries
- LATCA
Stored SMILES
COc1ccc(NC(=O)CC2C(=O)Nc3ccccc3C=2O)cc1Matched external records: PubChem 54678205
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALDH1A1 · Aldehyde dehydrogenase 1A1 | ChEMBL | ALD5 YER073W (ortholog_many2many); ALD3 YMR169C (ortholog_many2many); ALD2 YMR170C (ortholog_many2many); ALD4 YOR374W (ortholog_many2many); ALD6 YPL061W (ortholog_many2many) |
| ATXN2 · Ataxin-2 | ChEMBL | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL | YJR119C (ortholog_one2many) |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-N-(4-methoxyphenyl)acetamide research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.