CHEMGRID MOLECULE CARD
3-methyl-6-(piperidin-1-yl)-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione
3-methyl-6-(piperidin-1-yl)-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT026B09
Explore activity & SONAR![Chemical structure of 3-methyl-6-(piperidin-1-yl)-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione](/structure-thumbnails/LATCA/LA/LAT026B09.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- LAT026B09
- Molecular formula
- C22H20N2O2
- InChIKey
- ZMXVWFFEPNMQNW-UHFFFAOYSA-N
- Libraries
- LATCA
Stored SMILES
CN1C(=O)C=c2c3ccccc3c(=O)c3c(ccc1c23)N1CCCCC1Matched external records: PubChem 1961333
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B | ChEMBL | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| EYA2 · Protein phosphatase EYA2 | ChEMBL | No stored yeast mapping |
| fadD28 · Long-chain-fatty-acid--AMP ligase FadD28 | ChEMBL | No stored yeast mapping |
| FGB · Fibrinogen beta chain | ChEMBL | No stored yeast mapping |
| gld-1 · Female germline-specific tumor suppressor gld-1 | ChEMBL | No stored yeast mapping |
| GLP1R · Glucagon-like peptide 1 receptor | ChEMBL | No stored yeast mapping |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL | YJR119C (ortholog_one2many) |
| L3MBTL1 · Lethal(3)malignant brain tumor-like protein 1 | ChEMBL | No stored yeast mapping |
| S100A4 · Protein S100-A4 | ChEMBL | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
| THRB · Thyroid hormone receptor beta | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 3-methyl-6-(piperidin-1-yl)-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.