CHEMGRID MOLECULE CARD

S001 C05

S001 C05 in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LAT024F08

Explore activity & SONAR

Chemical structure of S001 C05 — Stored molecular structure

5Screened assays

0Significant assay responses

11Source-labelled target records

Identity and chemistry

ChemGrid identifier: LAT024F08
Molecular formula: Br2C15H17NO2S2
InChIKey: WVXUIXINYPYVRB-UHFFFAOYSA-N
Libraries: LATCA
Other recorded names: [2-(3,5-Dibromo-2-hydroxyphenyl)-2-oxoethyl] 3-methylpiperidine-1-carbodithioate

Stored SMILES

CC1CCCN(C1)C(=S)SCC(=O)c1cc(Br)cc(Br)c1O

Matched external records: PubChem 3114299

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
ATXN2 · Ataxin-2	ChEMBL	No stored yeast mapping
FEN1 · Flap endonuclease 1	ChEMBL	RAD27 YKL113C (ortholog_one2one)
MAPT · Microtubule-associated protein tau	ChEMBL	No stored yeast mapping
MEN1 · Menin/Histone-lysine N-methyltransferase MLL	ChEMBL	No stored yeast mapping
MPI · Mannose-6-phosphate isomerase	ChEMBL	PMI40 YER003C (ortholog_one2one)
POLB · DNA polymerase beta	ChEMBL	No stored yeast mapping
POLI · DNA polymerase iota	ChEMBL	No stored yeast mapping
POLK · DNA polymerase kappa	ChEMBL	TRF5 YNL299W (ortholog_many2many); PAP2 YOL115W (ortholog_many2many)
TAAR1 · Trace amine-associated receptor 1	ChEMBL	No stored yeast mapping
TDP1 · Tyrosyl-DNA phosphodiesterase 1	ChEMBL	TDP1 YBR223C (ortholog_one2one)
WRN · Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN	ChEMBL	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete S001 C05 research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.