ChemGrid

CHEMGRID MOLECULE CARD

Novel

Novel in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LAT017A11

Explore activity & SONAR
Chemical structure of Novel
Stored molecular structure
5Screened assays
0Significant assay responses
10Source-labelled target records

Identity and chemistry

ChemGrid identifier
LAT017A11
Molecular formula
C15H10O4
InChIKey
DHXYEHZZPWRLIG-UHFFFAOYSA-N
Libraries
LATCA
Other recorded names
3-Oxo-2,3-dihydro-1-benzofuran-6-yl benzoate
Stored SMILESO=C1COc2cc(OC(=O)c3ccccc3)ccc12

Matched external records: PubChem 732046

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
Luciferin 4-monooxygenaseChEMBLNo stored yeast mapping
CBX1 · Chromobox protein homolog 1ChEMBLNo stored yeast mapping
ESR2 · Estrogen receptor betaChEMBLNo stored yeast mapping
EYA2 · Protein phosphatase EYA2ChEMBLNo stored yeast mapping
HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2ChEMBLNo stored yeast mapping
KMT2A · Histone-lysine N-methyltransferase 2AChEMBLNo stored yeast mapping
KPNB1 · Importin subunit beta-1/Snurportin-1ChEMBLKAP95 YLR347C (ortholog_one2one)
MAPT · Microtubule-associated protein tauChEMBLNo stored yeast mapping
MEN1 · Menin/Histone-lysine N-methyltransferase MLLChEMBLNo stored yeast mapping
WRN · Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete Novel research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.