CHEMGRID MOLECULE CARD
Novel
Novel in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT016G04
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT016G04
- Molecular formula
- C20H21N3O4S
- InChIKey
- DRTXCSRDYDTUEB-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- 5-Cyano-6-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]sulfanyl-4-isobutyl-2-methyl-pyridine-3-carboxamide
Stored SMILES
CC(C)Cc1c(C#N)c(SCC(=O)c2ccc(O)c(O)c2)nc(C)c1C(N)=OMatched external records: PubChem 2264803
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| pol · Human immunodeficiency virus type 1 integrase | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Novel research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.