CHEMGRID MOLECULE CARD
Novel
Novel in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT015F10
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT015F10
- Molecular formula
- C17H15N3O3S
- InChIKey
- LQOGSLQLACDVCQ-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- 1-(3,4-Dihydroxyphenyl)-2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]ethanone
Stored SMILES
Cn1c(SCC(=O)c2ccc(O)c(O)c2)nnc1c1ccccc1Matched external records: PubChem 838842
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALPG · Alkaline phosphatase, germ cell type | ChEMBL | No stored yeast mapping |
| ALPL · Alkaline phosphatase, tissue-nonspecific isozyme | ChEMBL | PHO8 YDR481C (ortholog_one2many) |
| BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B | ChEMBL | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| CGA · Glycoprotein hormones alpha chain | ChEMBL | No stored yeast mapping |
| fba · Fructose-bisphosphate aldolase | ChEMBL | SMI1 YGR229C (ortholog_one2many) |
| ffp · 4'-phosphopantetheinyl transferase ffp | ChEMBL | No stored yeast mapping |
| GAA · Lysosomal alpha-glucosidase | ChEMBL | ROT2 YBR229C (ortholog_one2many) |
| GNAS · Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | ChEMBL | GPA2 YER020W (ortholog_many2many); GPA1 YHR005C (ortholog_many2many) |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL | No stored yeast mapping |
| PLAA · Phospholipase A-2-activating protein | ChEMBL | DOA1 YKL213C (ortholog_one2one) |
| TGR · Thioredoxin glutathione reductase | ChEMBL | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Novel research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.