CHEMGRID MOLECULE CARD
Novel
Novel in ChemGrid: 5 screened assays, 5 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT013F07
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT013F07
- Molecular formula
- C25H31N3O
- InChIKey
- QFVDKARCPMTZCS-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- C.I. 42555:1
Stored SMILES
CN(C)c1ccc(cc1)C(O)(c1ccc(cc1)N(C)C)c1ccc(cc1)N(C)CMatched external records: PubChem 68050
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 5 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| wt24h | LATCA | 4932 | -25.06 |
| pdr24h | LATCA | 4932 | -21.01 |
| pdr22h | LATCA | 4932 | -18.14 |
| wt18h | LATCA | 4932 | -15.44 |
| pdr18h | LATCA | 4932 | -11.16 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ht1 · Hexose transporter 1 | ChEMBL | No stored yeast mapping |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
| LmGT2 · Glucose transporter | ChEMBL | No stored yeast mapping |
| SLC2A1 · Solute carrier family 2, facilitated glucose transporter member 1 | ChEMBL | YBR241C (ortholog_many2many); MAL31 YBR298C (ortholog_many2many); RGT2 YDL138W (ortholog_many2many); SNF3 YDL194W (ortholog_many2many); HXT15 YDL245C (ortholog_many2many); MPH2 YDL247W (ortholog_many2many); HXT7 YDR342C (ortholog_many2many); HXT6 YDR343C (ortholog_many2many); HXT3 YDR345C (ortholog_many2many); HXT13 YEL069C (ortholog_many2many); HXT10 YFL011W (ortholog_many2many); VPS73 YGL104C (ortholog_many2many); MAL11 YGR289C (ortholog_many2many); HXT4 YHR092C (ortholog_many2many); HXT1 YHR094C (ortholog_many2many); HXT5 YHR096C (ortholog_many2many); HXT8 YJL214W (ortholog_many2many); HXT9 YJL219W (ortholog_many2many); HXT16 YJR158W (ortholog_many2many); MPH3 YJR160C (ortholog_many2many); GAL2 YLR081W (ortholog_many2many); HXT2 YMR011W (ortholog_many2many); HXT17 YNR072W (ortholog_many2many); HXT11 YOL156W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Novel research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.