CHEMGRID MOLECULE CARD
Luteolin
Luteolin in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT006F11
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT006F11
- Molecular formula
- C15H10O6
- InChIKey
- IQPNAANSBPBGFQ-UHFFFAOYSA-N
- Libraries
- LATCA
Stored SMILES
Oc1cc(O)c2C(=O)C=C(Oc2c1)c1ccc(O)c(O)c1Matched external records: PubChem 5280445
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| CA12 · Carbonic anhydrase 12 | ChEMBL | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL | No stored yeast mapping |
| CA7 · Carbonic anhydrase 7 | ChEMBL | No stored yeast mapping |
| CSNK2B · Casein kinase 2 | ChEMBL | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL | No stored yeast mapping |
| CYP1B1 · Cytochrome P450 1B1 | ChEMBL | No stored yeast mapping |
| DPP4 · Dipeptidyl peptidase 4 | ChEMBL | DAP2 YHR028C (ortholog_one2one) |
| HIF1A · Hypoxia-inducible factor 1-alpha | ChEMBL | No stored yeast mapping |
| MKNK1 · MAP kinase-interacting serine/threonine-protein kinase 1 | ChEMBL | No stored yeast mapping |
| SLC16A1 · Monocarboxylate transporter 1 | ChEMBL | MCH4 YOL119C (ortholog_many2many); MCH5 YOR306C (ortholog_many2many) |
| TTR · Transthyretin | ChEMBL | No stored yeast mapping |
| Cruzipain | ChEMBL analogue | No stored yeast mapping |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL analogue | No stored yeast mapping |
| ALOX15B · Polyunsaturated fatty acid lipoxygenase ALOX15B | ChEMBL analogue | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL analogue | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL analogue | No stored yeast mapping |
| CA7 · Carbonic anhydrase 7 | ChEMBL analogue | No stored yeast mapping |
| CSNK2B · Casein kinase 2 | ChEMBL analogue | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL analogue | No stored yeast mapping |
| CYP1B1 · Cytochrome P450 1B1 | ChEMBL analogue | No stored yeast mapping |
| DPP4 · Dipeptidyl peptidase 4 | ChEMBL analogue | DAP2 YHR028C (ortholog_one2one) |
| FTO · Alpha-ketoglutarate-dependent dioxygenase FTO | ChEMBL analogue | No stored yeast mapping |
| HIF1A · Hypoxia-inducible factor 1-alpha | ChEMBL analogue | No stored yeast mapping |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL analogue | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL analogue | YJR119C (ortholog_one2many) |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| MKNK1 · MAP kinase-interacting serine/threonine-protein kinase 1 | ChEMBL analogue | No stored yeast mapping |
| PIM1 · Serine/threonine-protein kinase pim-1 | ChEMBL analogue | PIM1 YBL022C (ortholog_one2many) |
| POLK · DNA polymerase kappa | ChEMBL analogue | TRF5 YNL299W (ortholog_many2many); PAP2 YOL115W (ortholog_many2many) |
| PTPRS · Receptor-type tyrosine-protein phosphatase S | ChEMBL analogue | No stored yeast mapping |
First 30 of 34 target records; open the interactive profile for further evidence.
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Luteolin research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.