CHEMGRID MOLECULE CARD
3,4-Dihydroxybenzoic Acid
3,4-Dihydroxybenzoic Acid in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT005F05
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT005F05
- Molecular formula
- C7H6O4
- InChIKey
- YQUVCSBJEUQKSH-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- Protocatechuic Acid
Stored SMILES
OC(=O)c1ccc(O)c(O)c1Matched external records: PubChem 72
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ca · Carbonic anhydrase | ChEMBL | No stored yeast mapping |
| CA1 · Carbonic anhydrase 1 | ChEMBL | No stored yeast mapping |
| CA14 · Carbonic anhydrase 14 | ChEMBL | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL | No stored yeast mapping |
| CTSL · Procathepsin L | ChEMBL | No stored yeast mapping |
| GLS · Glutaminase kidney isoform, mitochondrial | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| M18AAP · Aspartyl aminopeptidase | ChEMBL | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| RAPGEF3 · Rap guanine nucleotide exchange factor 3 | ChEMBL | LTE1 YAL024C (ortholog_many2many); CDC25 YLR310C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 3,4-Dihydroxybenzoic Acid research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.