CHEMGRID MOLECULE CARD
Diuron
Diuron in ChemGrid: 5 screened assays, 1 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT005F03
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT005F03
- Molecular formula
- C9Cl2H10N2O
- InChIKey
- XMTQQYYKAHVGBJ-UHFFFAOYSA-N
- Libraries
- LATCA
Stored SMILES
CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1Matched external records: PubChem 3120
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 1 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| wt18h | LATCA | 4932 | -4.32 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| AHR · Aryl hydrocarbon receptor | ChEMBL | No stored yeast mapping |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL | No stored yeast mapping |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL | No stored yeast mapping |
| petD · Cytochrome b6-f complex subunit 4 | ChEMBL | No stored yeast mapping |
| PPX1 · Protoporphyrinogen IX oxidase | ChEMBL | No stored yeast mapping |
| psbA · Photosystem II protein D1 | ChEMBL | No stored yeast mapping |
| psbA · Photosystem Q(B) protein | ChEMBL | No stored yeast mapping |
| AHR · Aryl hydrocarbon receptor | ChEMBL analogue | No stored yeast mapping |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL analogue | No stored yeast mapping |
| petD · Cytochrome b6-f complex subunit 4 | ChEMBL analogue | No stored yeast mapping |
| PPX1 · Protoporphyrinogen IX oxidase | ChEMBL analogue | No stored yeast mapping |
| psbA · Photosystem II protein D1 | ChEMBL analogue | No stored yeast mapping |
| psbA · Photosystem Q(B) protein | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Diuron research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.