CHEMGRID MOLECULE CARD
RO 41-0960
RO 41-0960 in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT004G05
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT004G05
- Molecular formula
- C13FH8NO5
- InChIKey
- RQPAUNZYTYHKHA-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- (3,4-Dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone
Stored SMILES
[O-][N+](=O)c1cc(cc(O)c1O)C(=O)c1ccccc1FMatched external records: PubChem 3495594
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ATAD5 · ATPase family AAA domain-containing protein 5 | ChEMBL | No stored yeast mapping |
| CYP2C9 · Cytochrome P450 2C9 | ChEMBL | No stored yeast mapping |
| FEN1 · Flap endonuclease 1 | ChEMBL | RAD27 YKL113C (ortholog_one2one) |
| GFER · FAD-linked sulfhydryl oxidase ALR | ChEMBL | ERV1 YGR029W (ortholog_one2one) |
| GLS · Glutaminase kidney isoform, mitochondrial | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| HSPA5 · Endoplasmic reticulum chaperone BiP | ChEMBL | No stored yeast mapping |
| NFKB1 · Nuclear factor NF-kappa-B p105 subunit | ChEMBL | No stored yeast mapping |
| PTH1R · Parathyroid hormone/parathyroid hormone-related peptide receptor | ChEMBL | No stored yeast mapping |
| RECQL · ATP-dependent DNA helicase Q1 | ChEMBL | No stored yeast mapping |
| SNCA · Alpha-synuclein | ChEMBL | No stored yeast mapping |
| TTR · Transthyretin | ChEMBL | No stored yeast mapping |
| ATAD5 · ATPase family AAA domain-containing protein 5 | ChEMBL analogue | No stored yeast mapping |
| CYP2C9 · Cytochrome P450 2C9 | ChEMBL analogue | No stored yeast mapping |
| FEN1 · Flap endonuclease 1 | ChEMBL analogue | RAD27 YKL113C (ortholog_one2one) |
| GFER · FAD-linked sulfhydryl oxidase ALR | ChEMBL analogue | ERV1 YGR029W (ortholog_one2one) |
| GLS · Glutaminase kidney isoform, mitochondrial | ChEMBL analogue | No stored yeast mapping |
| GMNN · Geminin | ChEMBL analogue | No stored yeast mapping |
| HSPA5 · Endoplasmic reticulum chaperone BiP | ChEMBL analogue | No stored yeast mapping |
| NFKB1 · Nuclear factor NF-kappa-B p105 subunit | ChEMBL analogue | No stored yeast mapping |
| PTH1R · Parathyroid hormone/parathyroid hormone-related peptide receptor | ChEMBL analogue | No stored yeast mapping |
| RECQL · ATP-dependent DNA helicase Q1 | ChEMBL analogue | No stored yeast mapping |
| SNCA · Alpha-synuclein | ChEMBL analogue | No stored yeast mapping |
| TTR · Transthyretin | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete RO 41-0960 research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.