ChemGrid

CHEMGRID MOLECULE CARD

2-Aminonicotinic Acid

2-Aminonicotinic Acid in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LAT004F10

Explore activity & SONAR
Chemical structure of 2-Aminonicotinic Acid
Stored molecular structure
5Screened assays
0Significant assay responses
4Source-labelled target records

Identity and chemistry

ChemGrid identifier
LAT004F10
Molecular formula
C6H6N2O2
InChIKey
KPIVDNYJNOPGBE-UHFFFAOYSA-N
Libraries
LATCA
Other recorded names
2-Aminonicotinic acid
Stored SMILESNc1ncccc1C(O)=O

Matched external records: PubChem 72930

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
DAO · D-amino-acid oxidaseChEMBLNo stored yeast mapping
DDO · D-aspartate oxidaseChEMBLNo stored yeast mapping
GABRA1 · GABA-A receptor; anion channelChEMBLNo stored yeast mapping
NAPRT · Nicotinate phosphoribosyltransferaseChEMBLNPT1 YOR209C (ortholog_one2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete 2-Aminonicotinic Acid research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.