CHEMGRID MOLECULE CARD
P-Aminohippuric Acid
P-Aminohippuric Acid in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT004E10
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT004E10
- Molecular formula
- C9H10N2O3
- InChIKey
- HSMNQINEKMPTIC-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- p-Aminohippuric acid
Stored SMILES
Nc1ccc(cc1)C(=O)NCC(O)=OMatched external records: PubChem 2148
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Akr1b1 · Aldo-keto reductase family 1 member B1 | ChEMBL | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| ampC · Beta-lactamase | ChEMBL | No stored yeast mapping |
| HIF1A · Hypoxia-inducible factor 1-alpha | ChEMBL | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL | YJR119C (ortholog_one2many) |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| Pam · Peptidylglycine alpha-amidating monooxygenase | ChEMBL | No stored yeast mapping |
| RUNX1 · Runt-related transcription factor 1/Core-binding factor subunit beta | ChEMBL | No stored yeast mapping |
| Slc22a20 · Solute carrier family 22 member 20 | ChEMBL | No stored yeast mapping |
| Slc22a6 · Solute carrier family 22 member 6 | ChEMBL | PHO84 YML123C (ortholog_one2many) |
| SLC22A8 · Organic anion transporter 3 | ChEMBL | PHO84 YML123C (ortholog_one2many) |
| Akr1b1 · Aldo-keto reductase family 1 member B1 | ChEMBL analogue | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| ampC · Beta-lactamase | ChEMBL analogue | No stored yeast mapping |
| HIF1A · Hypoxia-inducible factor 1-alpha | ChEMBL analogue | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL analogue | YJR119C (ortholog_one2many) |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| Pam · Peptidylglycine alpha-amidating monooxygenase | ChEMBL analogue | No stored yeast mapping |
| RUNX1 · Runt-related transcription factor 1/Core-binding factor subunit beta | ChEMBL analogue | No stored yeast mapping |
| Slc22a20 · Solute carrier family 22 member 20 | ChEMBL analogue | No stored yeast mapping |
| Slc22a6 · Solute carrier family 22 member 6 | ChEMBL analogue | PHO84 YML123C (ortholog_one2many) |
| SLC22A8 · Organic anion transporter 3 | ChEMBL analogue | PHO84 YML123C (ortholog_one2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete P-Aminohippuric Acid research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.