CHEMGRID MOLECULE CARD
Betain
Betain in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT004E08
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- LAT004E08
- Molecular formula
- C5H11NO2
- InChIKey
- KWIUHFFTVRNATP-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- Betaine
Stored SMILES
[O-]C(=O)C[N+](C)(C)CMatched external records: PubChem 247
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| rep · Replicase polyprotein 1ab | ChEMBL | No stored yeast mapping |
| SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | ChEMBL | No stored yeast mapping |
| ALDH1A1 · Aldehyde dehydrogenase 1A1 | ChEMBL analogue | ALD5 YER073W (ortholog_many2many); ALD3 YMR169C (ortholog_many2many); ALD2 YMR170C (ortholog_many2many); ALD4 YOR374W (ortholog_many2many); ALD6 YPL061W (ortholog_many2many) |
| ampC · Beta-lactamase | ChEMBL analogue | No stored yeast mapping |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| LMNA · Prelamin-A/C | ChEMBL analogue | No stored yeast mapping |
| MPHOSPH8 · M-phase phosphoprotein 8 | ChEMBL analogue | No stored yeast mapping |
| Pmp22 · Peripheral myelin protein 22 | ChEMBL analogue | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| TARDBP · TAR DNA-binding protein 43 | ChEMBL analogue | PIN4 YBL051C (ortholog_many2many) |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL analogue | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Betain research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.