ChemGrid

CHEMGRID MOLECULE CARD

ACC

ACC in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LAT003D03

Explore activity & SONAR
Chemical structure of ACC
Stored molecular structure
5Screened assays
0Significant assay responses
27Source-labelled target records

Identity and chemistry

ChemGrid identifier
LAT003D03
Molecular formula
C4H7NO2
InChIKey
PAJPWUMXBYXFCZ-UHFFFAOYSA-N
Libraries
LATCA
Other recorded names
1-Aminocyclopropane-1-carboxylic acid
Stored SMILESNC1(CC1)C(O)=O

Matched external records: PubChem 535

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
CBX1 · Chromobox protein homolog 1ChEMBLNo stored yeast mapping
Chrm1 · Muscarinic acetylcholine receptor M1ChEMBLNo stored yeast mapping
EHMT2 · Histone-lysine N-methyltransferase EHMT2ChEMBLSET2 YJL168C (ortholog_many2many)
ffp · 4'-phosphopantetheinyl transferase ffpChEMBLNo stored yeast mapping
Grin1 · Glutamate NMDA receptorChEMBLNo stored yeast mapping
pfk · ATP-dependent 6-phosphofructokinaseChEMBLNo stored yeast mapping
rep · Replicase polyprotein 1abChEMBLNo stored yeast mapping
Slc1a5 · Amino acid transporterChEMBLNo stored yeast mapping
TSHR · Thyrotropin receptorChEMBLNo stored yeast mapping
BLM · RecQ-like DNA helicase BLMChEMBL analogueSGS1 YMR190C (ortholog_one2one)
CBX1 · Chromobox protein homolog 1ChEMBL analogueNo stored yeast mapping
Chrm1 · Muscarinic acetylcholine receptor M1ChEMBL analogueNo stored yeast mapping
EHMT2 · Histone-lysine N-methyltransferase EHMT2ChEMBL analogueSET2 YJL168C (ortholog_many2many)
ffp · 4'-phosphopantetheinyl transferase ffpChEMBL analogueNo stored yeast mapping
GMNN · GemininChEMBL analogueNo stored yeast mapping
Grin1 · Glutamate NMDA receptorChEMBL analogueNo stored yeast mapping
KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2ChEMBL analogueNo stored yeast mapping
KDM4A · Lysine-specific demethylase 4AChEMBL analogueYJR119C (ortholog_one2many)
KDM4E · Lysine-specific demethylase 4EChEMBL analogueYJR119C (ortholog_one2many)
LMNA · Prelamin-A/CChEMBL analogueNo stored yeast mapping
MPHOSPH8 · M-phase phosphoprotein 8ChEMBL analogueNo stored yeast mapping
pfk · ATP-dependent 6-phosphofructokinaseChEMBL analogueNo stored yeast mapping
PMP22 · Peripheral myelin protein 22ChEMBL analogueNo stored yeast mapping
rep · Replicase polyprotein 1abChEMBL analogueNo stored yeast mapping
Slc1a5 · Amino acid transporterChEMBL analogueNo stored yeast mapping
TSHR · Thyrotropin receptorChEMBL analogueNo stored yeast mapping
Txnrd1 · Thioredoxin reductase 1, cytoplasmicChEMBL analogueTRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete ACC research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.