CHEMGRID MOLECULE CARD
7-Cyclopentyl-5-(4-Phenoxy)Phenyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ylamine
7-Cyclopentyl-5-(4-Phenoxy)Phenyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ylamine in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
LAT003B09
Explore activity & SONAR![Chemical structure of 7-Cyclopentyl-5-(4-Phenoxy)Phenyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ylamine](/structure-thumbnails/LATCA/LA/LAT003B09.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- LAT003B09
- Molecular formula
- C23H22N4O
- InChIKey
- FMETVQKSDIOGPX-UHFFFAOYSA-N
- Libraries
- LATCA
- Other recorded names
- 7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamine
Stored SMILES
Nc1ncnc2n(cc(c3ccc(Oc4ccccc4)cc3)c12)C1CCCC1Matched external records: PubChem 6603792
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| BTK · Tyrosine-protein kinase BTK | ChEMBL | No stored yeast mapping |
| EGFR · Epidermal growth factor receptor | ChEMBL | No stored yeast mapping |
| FYN · Tyrosine-protein kinase Fyn | ChEMBL | No stored yeast mapping |
| KDR · Vascular endothelial growth factor receptor 2 | ChEMBL | No stored yeast mapping |
| LCK · Tyrosine-protein kinase Lck | ChEMBL | No stored yeast mapping |
| LYN · Tyrosine-protein kinase Lyn | ChEMBL | No stored yeast mapping |
| nfo · Endonuclease 4 | ChEMBL | No stored yeast mapping |
| SRC · Proto-oncogene tyrosine-protein kinase Src | ChEMBL | No stored yeast mapping |
| TEK · Angiopoietin-1 receptor | ChEMBL | No stored yeast mapping |
| BTK · Tyrosine-protein kinase BTK | ChEMBL analogue | No stored yeast mapping |
| EGFR · Epidermal growth factor receptor | ChEMBL analogue | No stored yeast mapping |
| FYN · Tyrosine-protein kinase Fyn | ChEMBL analogue | No stored yeast mapping |
| KDR · Vascular endothelial growth factor receptor 2 | ChEMBL analogue | No stored yeast mapping |
| LCK · Tyrosine-protein kinase Lck | ChEMBL analogue | No stored yeast mapping |
| LYN · Tyrosine-protein kinase Lyn | ChEMBL analogue | No stored yeast mapping |
| nfo · Endonuclease 4 | ChEMBL analogue | No stored yeast mapping |
| SRC · Proto-oncogene tyrosine-protein kinase Src | ChEMBL analogue | No stored yeast mapping |
| TEK · Angiopoietin-1 receptor | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 7-Cyclopentyl-5-(4-Phenoxy)Phenyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ylamine research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.