CHEMGRID MOLECULE CARD

Edoxudine

Edoxudine in ChemGrid: 5 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

LAT001E11

Explore activity & SONAR

Chemical structure of Edoxudine — Stored molecular structure

5Screened assays

0Significant assay responses

2Source-labelled target records

Identity and chemistry

ChemGrid identifier: LAT001E11
Molecular formula: C11H16N2O5
InChIKey: QFVJRGJHSZSRJI-UHFFFAOYSA-N
Libraries: LATCA
Other recorded names: 5-Ethyl-1-[4-hydroxy-3-(hydroxymethyl)-2-oxolanyl]pyrimidine-2,4-dione

Stored SMILES

CCC1=CN(C2OCC(O)C2CO)C(=O)N=C1O

Matched external records: PubChem 3201

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

5 measurements across 5 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	ChEMBL	No stored yeast mapping
SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	ChEMBL analogue	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete Edoxudine research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.