CHEMGRID MOLECULE CARD
ethyl 2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate
ethyl 2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
KM 01494
Explore activity & SONAR![Chemical structure of ethyl 2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate](/structure-thumbnails/Maybridge1000/KM/KM_01494.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- KM 01494
- Molecular formula
- C11H13N3O2
- InChIKey
- NPHJHMNEJZRHGG-UHFFFAOYSA-N
- Libraries
- Maybridge1000
- Other recorded names
- Ethyl 2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate
Stored SMILES
CCOC(=O)C1C=Nc2cc(C)nn2C=1CMatched external records: PubChem 2736420
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| GNAS · Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | ChEMBL | GPA2 YER020W (ortholog_many2many); GPA1 YHR005C (ortholog_many2many) |
| IDH1 · Isocitrate dehydrogenase [NADP] cytoplasmic | ChEMBL | IDP1 YDL066W (ortholog_many2many); IDP2 YLR174W (ortholog_many2many); IDP3 YNL009W (ortholog_many2many) |
| PTH1R · Parathyroid hormone/parathyroid hormone-related peptide receptor | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ethyl 2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.