CHEMGRID MOLECULE CARD
[4-(2-methoxyphenyl)piperazino](2-thienyl)methanone
[4-(2-methoxyphenyl)piperazino](2-thienyl)methanone in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
JFD 01728
Explore activity & SONARIdentity and chemistry
- ChemGrid identifier
- JFD 01728
- Molecular formula
- C16H18N2O2S
- InChIKey
- OQQADZFNFNHIJO-UHFFFAOYSA-N
- Libraries
- Maybridge1000
- Other recorded names
- 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine
Stored SMILES
COc1ccccc1N1CCN(CC1)C(=O)c1sccc1Matched external records: PubChem 694533
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| GNAS · Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | ChEMBL | GPA2 YER020W (ortholog_many2many); GPA1 YHR005C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete [4-(2-methoxyphenyl)piperazino](2-thienyl)methanone research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.