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CHEMGRID MOLECULE CARD

methyl 2-[(7-methylthieno[3,2-d]pyrimidin-4-yl)thio]acetate

methyl 2-[(7-methylthieno[3,2-d]pyrimidin-4-yl)thio]acetate in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

GK 01655

Explore activity & SONAR
Chemical structure of methyl 2-[(7-methylthieno[3,2-d]pyrimidin-4-yl)thio]acetate
Stored molecular structure
50Screened assays
0Significant assay responses
2Source-labelled target records

Identity and chemistry

ChemGrid identifier
GK 01655
Molecular formula
C10H10N2O2S2
InChIKey
DJOSLIPUXGYBQR-UHFFFAOYSA-N
Libraries
Maybridge1000
Other recorded names
Methyl 2-[(7-methylthieno[3,2-d]pyrimidin-4-yl)thio]acetate
Stored SMILESCOC(=O)CSc1ncnc2c(C)csc12

Matched external records: PubChem 2777588

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
Luciferin 4-monooxygenaseChEMBLNo stored yeast mapping
GNAS · Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortChEMBLGPA2 YER020W (ortholog_many2many); GPA1 YHR005C (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete methyl 2-[(7-methylthieno[3,2-d]pyrimidin-4-yl)thio]acetate research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.