CHEMGRID MOLECULE CARD
1-(4`-acetyl[1,1`-biphenyl]-4-yl)ethan-1-one
1-(4`-acetyl[1,1`-biphenyl]-4-yl)ethan-1-one in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
BTB 09791
Explore activity & SONAR![Chemical structure of 1-(4`-acetyl[1,1`-biphenyl]-4-yl)ethan-1-one](/structure-thumbnails/Maybridge1000/BT/BTB_09791.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- BTB 09791
- Molecular formula
- C16H14O2
- InChIKey
- YSTSBXDVNKYPTR-UHFFFAOYSA-N
- Libraries
- Maybridge1000
- Other recorded names
- 4,4'-Diacetylbiphenyl
Stored SMILES
CC(=O)c1ccc(cc1)c1ccc(cc1)C(C)=OMatched external records: PubChem 301558
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Luciferin 4-monooxygenase | ChEMBL analogue | No stored yeast mapping |
| BRCA1 · Breast cancer type 1 susceptibility protein | ChEMBL analogue | No stored yeast mapping |
| CBX1 · Chromobox protein homolog 1 | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| GMNN · Geminin | ChEMBL analogue | No stored yeast mapping |
| L3MBTL1 · Lethal(3)malignant brain tumor-like protein 1 | ChEMBL analogue | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| Rorc · Nuclear receptor ROR-gamma | ChEMBL analogue | No stored yeast mapping |
| SMN1 · Survival motor neuron protein | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 1-(4`-acetyl[1,1`-biphenyl]-4-yl)ethan-1-one research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.