CHEMGRID MOLECULE CARD

N-(4-acetamidophenyl)-2-[(8-bromo-5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetamide

N-(4-acetamidophenyl)-2-[(8-bromo-5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetamide in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

6290-0061

Explore activity & SONAR

Chemical structure of N-(4-acetamidophenyl)-2-[(8-bromo-5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetamide — Stored molecular structure

3Screened assays

0Significant assay responses

5Source-labelled target records

Identity and chemistry

ChemGrid identifier: 6290-0061
Molecular formula: BrC20H17N6O2S
InChIKey: QWMNBFSPVMFCPO-UHFFFAOYSA-N
Libraries: ChemDiv-Kinase

Stored SMILES

Cn1c2ccc(Br)cc2c2nnc(SCC(=O)Nc3ccc(NC(C)=O)cc3)nc12

Matched external records: PubChem 2945476

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
ampC · Beta-lactamase	ChEMBL	No stored yeast mapping
GALC · Galactocerebrosidase	ChEMBL	No stored yeast mapping
MAPT · Microtubule-associated protein tau	ChEMBL	No stored yeast mapping
POLB · DNA polymerase beta	ChEMBL	No stored yeast mapping
POLI · DNA polymerase iota	ChEMBL	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete N-(4-acetamidophenyl)-2-[(8-bromo-5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetamide research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.