CHEMGRID MOLECULE CARD
4-[[Cyclohexyl(methyl)amino]methyl]-3-hydroxybenzo[c]chromen-6-one
4-[[Cyclohexyl(methyl)amino]methyl]-3-hydroxybenzo[c]chromen-6-one in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
3931-2396
Explore activity & SONAR![Chemical structure of 4-[[Cyclohexyl(methyl)amino]methyl]-3-hydroxybenzo[c]chromen-6-one](/structure-thumbnails/ChemDiv-Kinase/39/3931-2396.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- 3931-2396
- Molecular formula
- C21H23NO3
- InChIKey
- YQIBCBWHGJLCTN-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
CN(Cc1c(O)ccc2c1OC(=O)c1ccccc12)C1CCCCC1Matched external records: PubChem 5389209
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B | ChEMBL | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL | YJR119C (ortholog_one2many) |
| KMT2A · Histone-lysine N-methyltransferase 2A | ChEMBL | No stored yeast mapping |
| MEN1 · Menin/Histone-lysine N-methyltransferase MLL | ChEMBL | No stored yeast mapping |
| MPI · Mannose-6-phosphate isomerase | ChEMBL | PMI40 YER003C (ortholog_one2one) |
| NSD2 · Histone-lysine N-methyltransferase NSD2 | ChEMBL | No stored yeast mapping |
| PTH1R · Parathyroid hormone/parathyroid hormone-related peptide receptor | ChEMBL | No stored yeast mapping |
| SMAD3 · Mothers against decapentaplegic homolog 3 | ChEMBL | No stored yeast mapping |
| SMN1 · Survival motor neuron protein | ChEMBL | No stored yeast mapping |
| TARDBP · TAR DNA-binding protein 43 | ChEMBL | PIN4 YBL051C (ortholog_many2many) |
| TRPV1 · Transient receptor potential cation channel subfamily V member 1 | ChEMBL | YVC1 YOR087W (ortholog_one2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 4-[[Cyclohexyl(methyl)amino]methyl]-3-hydroxybenzo[c]chromen-6-one research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.