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2-[[5-(N-ethylanilino)-[1,2,5]oxadiazolo[3,4-b]pyrazin-6-yl]amino]ethanol

2-[[5-(N-ethylanilino)-[1,2,5]oxadiazolo[3,4-b]pyrazin-6-yl]amino]ethanol in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

3448-0270

Explore activity & SONAR
Chemical structure of 2-[[5-(N-ethylanilino)-[1,2,5]oxadiazolo[3,4-b]pyrazin-6-yl]amino]ethanol
Stored molecular structure
3Screened assays
0Significant assay responses
3Source-labelled target records

Identity and chemistry

ChemGrid identifier
3448-0270
Molecular formula
C14H16N6O2
InChIKey
GWOUHSZBPLUEPW-UHFFFAOYSA-N
Libraries
ChemDiv-Kinase
Stored SMILESCCN(c1ccccc1)c1nc2nonc2nc1NCCO

Matched external records: PubChem 1964932

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
MAPK1 · Mitogen-activated protein kinase 1ChEMBLSLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many)
MSRA · Mitochondrial peptide methionine sulfoxide reductaseChEMBLMXR1 YER042W (ortholog_one2one)
POLI · DNA polymerase iotaChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete 2-[[5-(N-ethylanilino)-[1,2,5]oxadiazolo[3,4-b]pyrazin-6-yl]amino]ethanol research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.