CHEMGRID MOLECULE CARD
1-[4,6-Bis(dimethylamino)-1,3,5-triazin-2-yl]-3-(4-chlorophenyl)-2-iminoimidazolidin-4-one
1-[4,6-Bis(dimethylamino)-1,3,5-triazin-2-yl]-3-(4-chlorophenyl)-2-iminoimidazolidin-4-one in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
3379-0694
Explore activity & SONAR![Chemical structure of 1-[4,6-Bis(dimethylamino)-1,3,5-triazin-2-yl]-3-(4-chlorophenyl)-2-iminoimidazolidin-4-one](/structure-thumbnails/ChemDiv-Kinase/33/3379-0694.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- 3379-0694
- Molecular formula
- C16ClH19N8O
- InChIKey
- FRHTZFCGXMPDOI-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
CN(C)c1nc(nc(n1)N1CC(=O)N(C1=N)c1ccc(Cl)cc1)N(C)CMatched external records: PubChem 1047079
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALDH1A1 · Aldehyde dehydrogenase 1A1 | ChEMBL analogue | ALD5 YER073W (ortholog_many2many); ALD3 YMR169C (ortholog_many2many); ALD2 YMR170C (ortholog_many2many); ALD4 YOR374W (ortholog_many2many); ALD6 YPL061W (ortholog_many2many) |
| CBX1 · Chromobox protein homolog 1 | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 1-[4,6-Bis(dimethylamino)-1,3,5-triazin-2-yl]-3-(4-chlorophenyl)-2-iminoimidazolidin-4-one research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.