CHEMGRID MOLECULE CARD
4-[(4-Phenylphthalazin-1-yl)amino]benzenesulfonamide
4-[(4-Phenylphthalazin-1-yl)amino]benzenesulfonamide in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
3281-0878
Explore activity & SONAR![Chemical structure of 4-[(4-Phenylphthalazin-1-yl)amino]benzenesulfonamide](/structure-thumbnails/ChemDiv-Kinase/32/3281-0878.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- 3281-0878
- Molecular formula
- C20H16N4O2S
- InChIKey
- XJZGVGGXZKPYHH-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
NS(=O)(=O)c1ccc(Nc2nnc(c3ccccc3)c3ccccc23)cc1Matched external records: PubChem 2881615
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| CA1 · Carbonic anhydrase 1 | ChEMBL | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL | No stored yeast mapping |
| CA9 · Carbonic anhydrase 9 | ChEMBL | No stored yeast mapping |
| ENPP3 · Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | ChEMBL | NPP1 YCR026C (ortholog_many2many); NPP2 YEL016C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 4-[(4-Phenylphthalazin-1-yl)amino]benzenesulfonamide research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.