CHEMGRID MOLECULE CARD
ethyl 5-[(furan-2-ylcarbonyl)oxy]-1,2-dimethyl-1H-indole-3-carboxylate
ethyl 5-[(furan-2-ylcarbonyl)oxy]-1,2-dimethyl-1H-indole-3-carboxylate in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
3237-0982
Explore activity & SONAR![Chemical structure of ethyl 5-[(furan-2-ylcarbonyl)oxy]-1,2-dimethyl-1H-indole-3-carboxylate](/structure-thumbnails/ChemDiv-Kinase/32/3237-0982.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- 3237-0982
- Molecular formula
- C18H17NO5
- InChIKey
- OPKTZXIDVOFXRV-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3occc3)cc21Matched external records: PubChem 917257
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL | No stored yeast mapping |
| CYP2C19 · Cytochrome P450 2C19 | ChEMBL | DIT2 YDR402C (ortholog_one2many) |
| CYP2C9 · Cytochrome P450 2C9 | ChEMBL | No stored yeast mapping |
| CYP3A4 · Cytochrome P450 3A4 | ChEMBL | No stored yeast mapping |
| KAT2A · Histone acetyltransferase KAT2A | ChEMBL | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| SMPD1 · Sphingomyelin phosphodiesterase | ChEMBL | PPN1 YDR452W (ortholog_one2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ethyl 5-[(furan-2-ylcarbonyl)oxy]-1,2-dimethyl-1H-indole-3-carboxylate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.